Vampirella intervenes when her lover
Adam Van Helsing, having taken the transformative drug Hyde-25, attempts to
kill Samuel Bishop, aka the Jackass, whose own great-great-grandfather’s genes
were altered by exposure to the drug a century ago. Hyde-25
is originally from “Night of the Jackass,” a strip by Bruce Bezaire and Jose
Ortiz that appeared in the Warren magazine Eerie. Samuel Bishop, the great-great-grandson of
Claude Bishop from “Night of the Jackass,” first appeared in “Return of the
Jackass” by Tom Sniegoski, Jim Webb, and Steve Mitchell, Hyde-25 #0, Harris Comics, April 1995. The name
“Hyde-25” is derived from Dr. Henry Jekyll’s alter ego Edward Hyde.

The Crossover UniverseTM is a companion blog to the books Crossovers: A Secret Chronology of the World Volumes 1-2 by Win Scott Eckert, and the forthcoming Crossovers Expanded Volumes 1-2 by Sean Levin. Material excerpted from Crossovers Volumes 1 & 2 is © copyright 2010-2014 by Win Scott Eckert. All rights reserved. Material excerpted from Crossovers Expanded Volumes 1 & 2 is © copyright 2014-present by Sean Levin. All rights reserved.
Although Simon Green doesn't call it Hyde-25, a similar formula is referenced in both the Nightside and Secret Histories series
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